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R&D pipeline

China has a high incidence of end-stage renal disease (ESRD). According to the guidelines for screening, diagnosis and prevention of chronic kidney disease (CKD), the prevalence of adult CKD in China is about 10.8%, and there are nearly 130 million patients with CKD, of which nearly 30 million will develop into ESRD. Nevertheless, as the proportion of patients receiving maintenance dialysis is much lower than that of developed countries, the attention paid to therapeutic drugs in this field in China is relatively low, and the fast-growing market demand holds great market potential.

The immune system is involved in the occurrence and development of almost all human diseases. Low immunity may lead to reduced ability to fight infections, while an overreaction of the immune system may lead to allergies and autoimmune diseases such as systemic lupus erythematosus (SLE), nephropathies, and rheumatoid arthritis, among others. The therapeutic drugs we focus on in this area are immunosuppressive drugs.

  • 10.8%

    The prevalence of chronic kidney disease in Chinese adults is about 10.8%
  • 130million

    Nearly 130 million patients with chronic kidney disease
  • 30million

    Nearly 30 million patients will develop end-stage renal disease

R&D Direction

With research in the areas of nephropathy and related diseases and immune system diseases, we are committed to addressing unmet clinical needs while selecting generic drugs that can become first-to-market for rapid genericization.

R&D Strategy

Self-development can be accompanied by simultaneous acquisition and merger of R&D entities and investment in R&D teams to gain access to product ownership.

R&D support

  • Australia REFORMPHARM
  • Ruijie Pharmaceutical
  • R&D direction selection

  • R&D support

  • R&D strategy

Founded in 2014, the company is located in the National Innovation Talent Cultivation Demonstration Base of Hi-Tech Park, Jiangning District, Nanjing, with a laboratory area of nearly 2,000 square meters, and is a company dedicated to the research and development of innovative drugs and high-end generics. The company's innovative drug R&D focuses on liver diseases, cancer treatment and autoimmune diseases; generic drug R&D mainly practices the system of marketing authorization holder (MAH), and has a quality management system for the whole life cycle of drugs. The company's core strategy is technology and innovation, with self-developed formulation technology platform and innovative drug R&D platform, and drug R&D based on the technology platform, constantly enriching the company's product line. The company's formulation technology platform owns skeleton tablet slow release technology, micro-pill slow and controlled release technology, Lipodose technology and innovative drug development technology.

  • R&D direction selection

  • R&D support

  • R&D strategy

R&D progress

project name
indication
Project evaluation CM&C Clinical study Declare Approved for listing
Nafamostat mesylate for injection
Anticoagulation of blood in extracorporeal circulation
Matemacrolate Capsules
Organ transplantation anti-rejection Lupus Nephritis
Lanthanum Carbonate Chewable Tablets
Chronic Kidney Disease Hyperphosphatemia
Tacrolimus Capsules
Organ transplantation anti-rejection
Nafurafine hydrochloride orally disintegrating
Hemodialysis Itchy Skin UP
D&R TTL
Spinal Cerebellar Degenerative Disease SCD
D&R NM
Stroke ALS
D&R NM
Acute Spinal Cord Injury
D&R NM
Prevention of post-ERCP pancreatitis